Impact of microbial genome completeness on metagenomic functional inference
Impact of microbial genome completeness on metagenomic functional inference
You can read the full article in ISME Communications here: https://doi.org/10.3389/fphys.2022.935870
Alterations in bacterial metabolites, cytokines, and mucosal integrity in the caecum of broilers caused by feed additives and host-related factors
Alterations in bacterial metabolites, cytokines, and mucosal integrity in the caecum of broilers caused by feed additives and host-related factors
You can read the full article in Frontiers in Physiology here: https://doi.org/10.3389/fphys.2022.935870
A strategic model of a host–microbe–microbe system reveals the importance of a joint host–microbe immune response to combat stress-induced gut dysbiosis
A strategic model of a host–microbe–microbe system reveals the importance of a joint host–microbe immune response to combat stress-induced gut dysbiosis
You can read the full article in Frontiers in Microbiology Journal
doi: 10.3389/fmicb.2022.912806
Novel strategies to improve chicken performance and welfare by unveiling host-microbiota interactions through hologenomics
Novel strategies to improve chicken performance and welfare by unveiling host-microbiota interactions through hologenomics
In this paper, we introduce the animal trials conducted with broiler chickens in the H2020 project HoloFood, and our strategy to implement hologenomic analyses in light of the initial results, which despite yielding negligible effects of tested feed additives, provide relevant information to understand how host genomic features, microbiota development dynamics and host-microbiota interactions shape animal welfare and performance.
You can read the full article in Frontiers Journal here: https://doi.org/10.1002/ggn2.202100065
Recovering High-Quality Host Genomes from Gut Metagenomic Data through Genotype Imputation
Recovering High-Quality Host Genomes from Gut Metagenomic Data through Genotype Imputation
A new research paper from HoloFood provides a 2 step approach to generate high quality host genomes from shotgun metagenomic datasets. This method allows researchers to utilise host DNA from metagenomic runs and impute genetic structure from host populations.
You can read the full article in Advance Genetics here: https://doi.org/10.1002/ggn2.202100065
"A holistic view of the organism and its microorganisms" - public article in Danish
"A holistic view of the organism and its microorganisms" - public article in Danish
Danish magazine Aktuel Naturvidenskab featured the HoloFood project in a recent article highlighting hologenomics. The article focuses on sustainable aquaculture as an example to communicate the science behind hologenomics to their audience.
You can read the full article in Danish here: https://aktuelnaturvidenskab.dk/find-artikel/nyeste-numre/3-2022/et-holistisk-syn-paa-organismen-og-dens-mikroorganismer
European Aquaculture Society March edition magazine
European Aquaculture Society March edition magazine
Building the industry-academia relationship is key to the future success of building a scientifically-informed future for aquaculture.
The article can be found here: https://www.aquaeas.eu/publications-new/eas-magazine
Microbiome “Inception”: an Intestinal Cestode Shapes a Hierarchy of Microbial Communities Nested within the Host
Microbiome “Inception”: an Intestinal Cestode Shapes a Hierarchy of Microbial Communities Nested within the Host
A new research article on endoparasite - host relationship in salmon by HoloFood researchers is published in mBio with some surprising insights. The results suggest that parasit cestodes may be themselves holobionts within the microbiomes of their fish host - emphasizing the importance of also considering microbes associated with parasites when studying instestinal parasitic infections.
You can read the full paper here: https://doi.org/10.1128/mbio.00679-22
Review: Disentangling host–microbiota complexity through hologenomics
A new review article in the journal Nature Review Genetics by HoloFood coordinators Tom Gilbert, Antton Alberdi and Morten Limborg is published. The review covers the field of hologenomics, the advantages and current limitations of such studies and how best to design a hologenomic research project.
You can read the full paper here: https://doi.org/10.1038/s41576-021-00421-0
Review: Development and Functional Properties of Intestinal Mucus Layer in Poultry
A new review article in the journal Frontiers in Immunology by PhD student Yada Duangnumsawang, Prof. Jürgen Zentek and Dr. Farshad Goodarzi Boroojeni from Freie Universität Berlin, explores the importance of the intestinal mucus in the poultry gut. The mucosal barrier of the gut is the first line of defence against the invasion of pathogens, supporting the colonization of beneficial bacteria and maintaining the proper environment for digestion. In spite of its great importance, little is known about the structure and functional properties of the intestinal mucus layer within the chicken gut. This review expands on our current understanding of this important intestinal mucus, the impact of age on the development of the cells that are a part of it as well as the dietary factors that impact them.
You can read the full paper here: https://doi.org/10.3389/fimmu.2021.745849
Research Article: Salmon gut microbiota correlates with disease infection status: potential for monitoring health in farmed animals
MSc student Davide Bozzi and researchers and industry partners from the HoloFood project have published a new research article on monitoring salmon health in response to disease and treatment to disease within aquaculture. The study, entitled 'Salmon gut microbiota correlates with disease infection status: potential for monitoring health in farmed animals' was published in Animal Microbiome Journal, and was a collaborative effort between academic and industry partners of the consortium.
Read the behind the behind-the-paper blog by clicking here
Or access the full paper: https://doi.org/10.1186/s42523-021-00096-2
Perspective Article: Holo-Omics: Integrated Host-Microbiota Multi-omics for Basic and Applied Biological Research
PhD student Lasse Nyholm Jessen and his colleagues from the HoloFood EU project and Center for Evolutionary Hologenomics at University of Copenhagen have published a perspective paper on the new possibilities of holo-omics in the open access journal iScience.
Read the relevant news article : https://ceh.ku.dk/news/2020/the-holo-omic-approach-opens-up-new-research-avenues/
Read more in the original open access paper: https://doi.org/10.1016/j.isci.2020.101414
